學術發表 - OBI Pharma 台灣浩鼎

2022.Jun.02

Prodrug

Safety, pharmacokinetics, and clinical activity of OBI-3424, an AKR1C3-activated prodrug, in patients with advanced or metastatic solid tumors: A phase 1 dose-escalation study.

2022.Apr.09

Vaccine

High Globo-H expression associated with poor survival of gastric cancer patients and enriched PD-L1 expression

2022.Apr.09

Prodrug

OBI-3424, an AKR1C3-activated prodrug, exhibits in vivo synergistic anti-tumor effect in combination with pembrolizumab by induction of immunogenic cell death

2021.Nov.04

Vaccine

The role of Globo H and SSEA-4 in the development and progression of cancer, and their potential as therapeutic targets

2021.Jul.15

Prodrug

A novel selective AKR1C3-activated prodrug AST-3424/OBI-3424 exhibits broad anti-tumor activity

2021.Jun.01

ADC

Preclinical Studies of OBI-999: A Novel Globo H–Targeting Antibody–Drug Conjugate

2021.Apr.10

Vaccine

Inhibitory activity of Globo-H and SSEA-4 on activated T cells

2021.Apr.10

Prodrug

Selective and Broad Anti-tumor Activity of AKR1C3-activated Prodrug AST-3424/OBI-3424

2021.Apr.10

ADC

Preclinical characterization of a novel SSEA4-targeting antibody drug conjugate, OBI-998

2020.Nov.19

Vaccine

A phase I cohort expansion trial of OBI-833 in non-small cell lung cancer patients