Announcement that the cumulative reduction of shareholding in major subsidiary, AP Biosciences, has reached more than 10%

1.Name of major subsidiary:AP Biosciences, Inc. (hereinafter referred to as “AP Biosciences”) 2.Cause of occurrence (reduce the percentage of shareholding (or capital contribution to) or lose control ):Reduce the percentage of shareholding 3.Method of shareholding (or capital contribution) reduction (Please specify the date, reason, method, reduction percentage, volume, unit price, and total amount each time): […]